Psychobiotics and the Manipulation of Bacteria–Gut–Brain Signals

Abstract Psychobiotics were previously defined as live bacteria (probiotics) which, when ingested, confer mental health benefits through interactions with commensal gut bacteria. We expand this definition to encompass prebiotics, which enhance the growth of beneficial gut bacteria. We review probiotic and prebiotic effects on emotional, cognitive, systemic, and neural variables relevant to health and disease.
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“Dirty Dozen” and “Clean Fifteen” Lists

Vast enclosed green fields of the finest organic produce.
The Environmental Working Group (EWG) comes up with a couple lists of popular fruits and vegetables consumed by Americans ranking the amount of pesticide contamination. These rankings are based off of commercially bought food and are general guidelines of what to buy organically. I personally recommend going to farmers markets and/or growing your own fruits
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Oral Contraceptives and Changes in Nutritional Requirements

Oral contraceptives and nutrional health.
Abstract Oral contraceptives (OCs) are a major class of prescription drug, used by a large proportion of women starting from early adolescence. Much research has been conducted to investigate the physiological changes that occur in women who take OCs. These include changes in general health as well as in nutritional needs. In terms of nutrition,
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β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares

Abstract Aging and lipotoxicity are two major risk factors for gout that are linked by the activation of the NLRP3 inflammasome. Neutrophil-mediated production of interleukin-1β (IL-1β) drives gouty flares that cause joint destruction, intense pain, and fever. However, metabolites that impact neutrophil inflammasome remain unknown. Here, we identified that ketogenic diet (KD) increases β-hydroxybutyrate (BHB)
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The Ketone Metabolite β-hydroxybutyrate Blocks NLRP3 Inflammasome–Mediated Inflammatory Disease

Abstract The ketone bodies β-hydroxybutyrate (BHB) and acetoacetate (AcAc) support mammalian survival during states of energy deficit by serving as alternative sources of ATP1. BHB levels are elevated by starvation, caloric restriction, high-intensity exercise, or the low-carbohydrate ketogenic diet2. Prolonged fasting reduces inflammation; however, the impact that ketones and other alternative metabolic fuels produced during
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Probiotics And Gut Health

Gut health is one of the foundations of health that is often dysfunctional and overlooked in many people in the United States. Gut health issues can manifest as many different signs and symptoms, including: anxiety, depression, skin disorders, bloating, bad breath (halitosis), brain fog, food sensitivities, and many other. One important aspect with gut health
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