The Ketone Metabolite β-hydroxybutyrate Blocks NLRP3 Inflammasome–Mediated Inflammatory Disease
Tuesday, June 12, 2018
Abstract The ketone bodies β-hydroxybutyrate (BHB) and acetoacetate (AcAc) support mammalian survival during states of energy deficit by serving as alternative sources of ATP1. BHB levels are elevated by starvation, caloric restriction, high-intensity exercise, or the low-carbohydrate ketogenic diet2. Prolonged fasting reduces inflammation; however, the impact that ketones and other alternative metabolic fuels produced during
- Published in Scientific Article
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