Dietary Fatty Acids and Susceptibility to Multiple Sclerosis
Monday, April 22, 2019
Summary: Incorporating short chain fatty acids (SCFAs) is a safe and potent add-on therapy for multiple sclerosis (MS). Abstract: BACKGROUND: The gut microbiome as well as dietary habits have recently been established as environmental contributors to the pathogenesis of multiple sclerosis (MS), a T-cell-mediated autoimmune disease of the central nervous system (CNS). OBJECTIVE: To summarize
- Published in Scientific Article
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SCFAs Train T Cells in the Gut to Fight Autoimmunity in the Brain
Monday, April 22, 2019
Summary: Short Chain Fatty Acids (SCFAs) produced by gut bacteria decreases autoimmunity (immune system attacking host tissue) against the brain. Abstract: In this issue of Immunity, Haghikia and colleagues (2015)demonstrate that dietary fatty acids, by modulating gut microbes and their metabolism, regulate mucosal immune cells to impact systemic immunity. Using this mechanism, dietary and bacteria-derived medium-chain and
- Published in Scientific Article