Systematic Genome Assessment of B-vitamin Biosynthesis Suggests Co-operation Among Gut Microbes
Wednesday, October 31, 2018
Summary Our gut microbiome is capable of synthesizing B vitamins. If there’s a B vitamin deficiency, it would be beneficial to work on gut bacteria to improve symptoms. Abstract The human gut microbiota supplies its host with essential nutrients, including B-vitamins. Using the PubSEED platform, we systematically assessed the genomes of 256 common human gut
- Published in Scientific Article
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Omega-3 Polyunsaturated Fatty Acids Time-Dependently Reduce Cell Viability and Oncogenic MicroRNA-21 Expression in Estrogen Receptor-Positive Breast Cancer Cells (MCF-7)
Monday, October 15, 2018
Abstract The omega-3 polyunsaturated fatty acid (n-3 PUFA), α-linolenic acid (ALA), and its metabolites, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), independently reduce the growth of breast cancer cells in vitro, but the mechanisms, which may involve microRNA (miRNA), are still unclear. The expression of the oncomiR, miR-21, is reduced by DHA treatment, but the
- Published in Scientific Article
Magnesium and the Regulation of Muscle Contraction
Monday, October 15, 2018
Summary Magnesium can help relax overly-contracted muscles. Abstract There are a variety of Ca2+ binding sites in muscle (e.g., troponin, parvalbumin, myosin, and calmodulin) that may play a role in the regulation of muscle contraction an other enzymatic processes. Since most of these proteins also bind Mg2+, it is important to consider the effect that
- Published in Scientific Article
Marine Fish Oil is More Potent than Plant-Based n-3 Polyunsaturated Fatty Acids in the Prevention of Mammary Tumors.
Monday, October 15, 2018
Abstract Marine-derived n-3 polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been shown to inhibit mammary carcinogenesis. However, evidence regarding plant-based α-linolenic acid (ALA), the major n-3 PUFA in the Western diet, remains equivocal. The objective of this study was to examine the effect of lifelong exposure to plant-
- Published in Scientific Article